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DESCRIPTION
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DESCRIPTION
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Package: CHAS
Title: Cell type deconvolution of bulk tissue histone acetylomes from epigenetic data
Version: 0.99.8
Description: CHAS is an R package which integrates cell sorted H3K27ac data to identify cell type-specific peaks in bulk tissue H3K27ac profiles. Using the cell type-specific H3K27ac peaks, one can then calculate cell type-specific acetylation scores to act as a proxy for cell type proportion in the bulk tissue sample.
Authors@R:
person(given = "Kitty",
family = "Murphy",
role = c("aut", "cre"),
email = "c.murphy19@ic.ac.uk",
comment = c(ORCID = "YOUR-ORCID-ID"))
biocViews:
Imports:
data.table,
dplyr,
edgeR,
GenomicRanges,
ggplot2,
ggpubr,
IRanges,
RColorBrewer,
Rsubread,
stringi,
tidyr,
tidyverse,
wesanderson,
ggpattern,
S4Vectors
License: GPL (>= 3) + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Depends:
R (>= 3.6.0)
Suggests:
testthat (>= 3.0.0)
Config/testthat/edition: 3