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Data normalized or not? #15

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vfriver opened this issue Jul 18, 2022 · 3 comments
Open

Data normalized or not? #15

vfriver opened this issue Jul 18, 2022 · 3 comments

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@vfriver
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vfriver commented Jul 18, 2022

Hi, thanks for your contribution. Congratulations
I have two doubts.

  1. You wrote different information in two places. I wanted to know if there is any error in any of them.
    In the article: The input expression matrix is assumed to have been properly normalized.
    Gituhub: Data is expected to be not normalized.
  2. I also made a KO and the FDR values came out of 0.999. Is there the possibility of choosing genes not by the FDR, but for fold change for example greater than 0.5?

Thanks for your time and help!

@vfriver vfriver changed the title Data normalized or nor? Data normalized or not? Jul 18, 2022
@nureenmz
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I would also like to know the answer for the first question. If the input countMatrix have already been normalized and QC-ed, how do I turn off QC? Setting QC=FALSE outputs an unused argument error. Thanks!

@dosorio
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dosorio commented Sep 29, 2022

Hi @B195515, you can install the latest version under development using remotes::install_github('cailab-tamu/scTenifoldKnk')

@seekning
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嗨,@B195515,你可以使用 remotes::install_github('cailab-tamu/scTenifoldKnk') 安装正在开发的最新版本

stupid

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