diff --git a/CHANGES/5967.bugfix b/CHANGES/5967.bugfix
new file mode 100644
index 0000000000..ebc7f81bc8
--- /dev/null
+++ b/CHANGES/5967.bugfix
@@ -0,0 +1,2 @@
+On the content-app, added ClientConnectionError (aiohttp) as an exception that can trigger
+a retry when streaming content from a Remote.
diff --git a/pulpcore/content/handler.py b/pulpcore/content/handler.py
index 651af1bc5e..60c5aa2c4a 100644
--- a/pulpcore/content/handler.py
+++ b/pulpcore/content/handler.py
@@ -5,7 +5,7 @@
 import re
 from gettext import gettext as _
 
-from aiohttp.client_exceptions import ClientResponseError
+from aiohttp.client_exceptions import ClientResponseError, ClientConnectionError
 from aiohttp.web import FileResponse, StreamResponse, HTTPOk
 from aiohttp.web_exceptions import (
     HTTPError,
@@ -815,6 +815,13 @@ async def _stream_content_artifact(self, request, response, content_artifact):
                 [pulpcore.plugin.models.ContentArtifact][] returned the binary data needed for
                 the client.
         """
+        # We should only retry with exceptions that happen before we receive any data
+        # and start streaming, as we can't rollback data if something happens after that.
+        RETRYABLE_EXCEPTIONS = (
+            ClientResponseError,
+            UnsupportedDigestValidationError,
+            ClientConnectionError,
+        )
 
         remote_artifacts = content_artifact.remoteartifact_set.select_related(
             "remote"
@@ -823,8 +830,7 @@ async def _stream_content_artifact(self, request, response, content_artifact):
             try:
                 response = await self._stream_remote_artifact(request, response, remote_artifact)
                 return response
-
-            except (ClientResponseError, UnsupportedDigestValidationError) as e:
+            except RETRYABLE_EXCEPTIONS as e:
                 log.warning(
                     "Could not download remote artifact at '{}': {}".format(
                         remote_artifact.url, str(e)