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210 public repositories
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Exemplary Protein PBPK Models
Modeling of published clinical itraconazole-pioglitazone-DDI studies for model evaluation
Physiologically-Based Pharmacokinetic (PBPK) Modeling of Fentanyl in Adults and Pediatric Patients
Whole-body PBPK model of ethinylestradiol as CYP1A2 DDI perpetrator drug
Updated
Apr 29, 2022
MATLAB
Whole-body parent-metabolite PBPK model of Clopidogrel for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 DDGI Predictions
Modeling of published clinical Clopidogrel-Bupropion-DDI studies for model evaluation
Modeling of published clinical gemfibrozil-pioglitazone-DDI studies for model evaluation
Updated
Nov 28, 2019
MATLAB
Modeling of published clinical Fluvoxamine-Omeprazole-DDI studies for model evaluation
Modeling of published clinical Omeprazole-Clopidogrel-DDI studies for model evaluation
Whole-body PBPK model of valproic acid including non-linear binding with albumin in adults, children and children with hypoalbuminemia.
Modeling of published clinical rifampicin-repaglinide-DDI studies for model evaluation
Modeling of published clinical Rifampicin-Verapamil-DDI studies for model evaluation
Whole-body PBPK model of moclobemide as a substrate and a moderate inhibitor of CYP2C19
Updated
Apr 29, 2022
MATLAB
Modeling of published clinical Fluvoxamine-Tizanidine-DDI studies for model evaluation
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