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Optimizing image processing in retinal prosthetics using human-in-the-loop optimization.

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Preferential Bayesian Optimization of retinal prosthetic stimulation

Requirements:

This software accompanies the paper : Fauvel T. and Chalk M, 2021, Human-in-the-loop optimization of retinal prostheses encoders. If you use this software, please reference it by citing this paper.

  • MATLAB

  • Psychtoolbox (Optional) http://psychtoolbox.org/download.html

  • Python 3

  • Pulse2percept, by Beyeler et al (2017):

    • You can either choose to work with the stable version (0.7.1) of pulse2percept or the latest one (0.8.0).
    • To use the stable release, use pip3 install pulse2percept
    • To install the latest release, use pip3 install git+https://github.com/pulse2percept/pulse2percept
  • BO_toolbox : Bayesian Optimization toolbox based on the GP_toolbox, https://github.com/TristanFauvel/BO_toolbox

  • GP_toolbox : Gaussian Process regression, classification, and preference learning, https://github.com/TristanFauvel/GP_toolbox

  • In the pulse2percept package installation folder, replace beyeler2019.py in /envs/pulse2percept-env/lib/python3.8/site-packages/pulse2percept/models with the file beyeler2019 in /p2p_modifications (if you use the stable p2p release) or by beyeler2019_modified_for_latest_p2p (if you use the latest release, and rename the file in beyeler2019).

  • Edit the file 'add_modules' according to the locations of the different folders on your computer.

  • To run an experiment : open('to_run_BO_experiment')

    • If you want to use Psychtoolbox : set use_ptb3 = 1
    • If you do not want to use Psychtoolbox : set use_ptb3 = 0

Run and analyze experiments:

  • Activate the Python environment in which pulse2percept is installed: conda activate pulse2percept_env
  • Launch Matlab with Psychtoolbox : ptb3-matlab
  • To launch experiments: to_run_BO_experiment.m
  • To analyze experiments: analysis_pipeline.m
  • Note that the first time you run vision tests, likelihoods used in the QUEST+ procedure will be computed, which can take a while (QPlikelihoods_E_VA.mat and QPlikelihoods_Snellen_VA.mat).

Organization :

* `Experiment`: scripts and functions to run the experiment described in the paper.
* `p2p_modifications` : contains modified p2p files required in order to run the experiment.
* `p2p_analysis`: code to perform the p2p analysis leading to the LN approximation described in the paper. Note that this analysis was performed on pulse2percept 0.5.0.
* `QuestPlus-master` : a Matlab implementation of the QUEST+ adaptive psychometric method, by Pete R Jones.
  • Stimuli : stimuli images used in the experiment

pulse2percept analysis:

  • The first thing to do is to compute M, the matrix of electrodes' projective fields: to do so, run to_compute_M.py.
  • To compare the output of the LN approximation and the original p2p model with random currents, use WN_electrodes.py.
  • To perform a visua comparison between the output of p2p and the LN approximation (in particular, for optimized stimuli) use optimized_code_stimuli.py.

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