Skip to content

summary data, scripts, and workflows for all species type strains in the bacterial genus Leptospira

License

Notifications You must be signed in to change notification settings

bacterial-genomics/leptospira_type_strains

Repository files navigation

Leptospira type strain work

This is a repository for summary data, scripts, and workflows to evaluate all species type strains in the bacterial genus Leptospira

Background on Leptospira

Taxonomy

  • The first reported observation of Leptospira (at the time not formally named but suggested as "(?Spirochaeta) interrogans") was in 1907 by the American physician Dr. A. M. Stimson (sole author), who saw it in kidneys from a yellow fever patient.
  • The effective publication describing this bacterial genus was in 1917 by the Japanese bacteriologist Dr. Hideyo Noguchi (sole author).

Genomics

  • The first public complete assembly of Leptospira on NCBI is from 2004 by the Sao Paulo state (Brazil) Consortium. The strain sequenced was Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
  • Unlike some taxa, the majority (85%) of Leptospira raw genome sequence data have corresponding assemblies on NCBI.
  • The genome consists of two circular chromosomes, roughly 4.6 Mbp in total size. For Illumina-only assemblies, 3.8 to 4.5 Mbp is a common size range observed from 85 to 120 contigs and 35% to 40% GC composition.

Data stored here

  • XLSX file listing of species type strains with several features for each:
    • effective publication year
    • 16S rRNA gene sequence locus tag
    • ppk1 gene sequence locus tag
    • RefSeq genome accession
    • taxonomic status
    • clade membership (i.e., pathogenic (P1, P2), saprophytic (S1, S2))

Resources

  1. The International Leptospirosis Society Inc. (ILS) webpage
  2. Renee L. Galloway, and Christopher A. Gulvik. 2023. Leptospira In: Carroll KC, Pfaller MA. Manual of Clinical Microbiology, 13th Edition. ASM Press, Washington, DC. doi: 10.1128/9781683670438.MCM.ch60 book chapter

About

summary data, scripts, and workflows for all species type strains in the bacterial genus Leptospira

Resources

License

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published

Languages