Steps implemented in NSP4_structure.ipynb
:
- PSI-BLAST to find homologous sequence
- Refining the target-template alignment
- Constructing the model by satisfying spatial restraints
- Evaluating model (and template) by generating DOPE profile
- Visualizing modelled structure
- Visualizing DOPE profiles of model and template
Submitted as an assignment for M. S. Madhusudhan's Bioinformatics course at IISER Pune.