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Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease of the adult, characterized by degeneration of motor neurons in the spinal cord, brain stem and motor cortex. There is no bio-informatic model of ALS.
Model of Motor Network during Parkinson's Disease and Deep Brain Stimulation. The model simulates LFP, EMG and associated force signals from the motor system. A multivariable adaptive control strategy is implemented in the model to control two biomarkers of Parkinsonian tremor and motor impairment symptoms.