SBML differential equation and chemical reaction model (Gillespie simulations) for Julia's SciML ModelingToolkit

This repository provides the MATLAB scripts for our quantitative systems pharmacology model published in Front. Bioeng. Biotechnol., where we conduct an in silico clinical trial in breast cancer using anti-PD-1, anti-CTLA-4 antibody and an epigenetic modulator.

Virtual population generation, fitting, and benchmarking.

From computationally intractable MATLAB code to ~1600x faster optimized C code

Source code for "Slow Delayed Rectifier Protects Against Arrhythmic Activity Across Multiple Species - A Computational Study"

PySB add-on providing domain-specific macros and models for empirical and mechanistic PK/PD modeling.

This repository contains the latest QSP platform for TNBC/NSCLC developed by the Popel Systems Biology Laboratory

Mechanistic Pan-Cancer Signaling Model

Source code for "Investigational treatments for COVID-19 may increase ventricular arrhythmia risk through drug interactions"